CMPD identified the victim as Tyrena Inman.
A second victim, an adult male, also was shot inside the hotel, police said. He was being treated at Carolinas Medical Center for an injury described by police as not life threatening.
CMPD did not say what led to the shooting, which was reported Sunday at 8:25 p.m. inside a room at an Extended Stay America hotel near Interstate 77 in southwest Charlotte.
No arrest was announced as of early Monday.
- Police were called to the 1500 block of Catherine Simmons Avenue in north Charlotte, where a 40-year-old man was found with a gunshot wound. The victim, identified by police as Daimeon Terrell Johnson, died at Carolinas Medical Center. No arrest was announced.
- Two people were shot, one fatally, in the 7100 block of Snow Lane in southeast Charlotte. Shalecia Shav’ea Williams, 21, died at Carolinas Medical Center. An adult male was being treated for injuries described as not life threatening. Police announced no arrest or motive for the shootings.
As of Monday, CMPD had investigated 43 homicides this year, up from 14 killings this same time in 2018.
CMPD leaders said Monday they were at a loss to explain the sudden rise.
Meanwhile, police on Friday made an arrest in the case of a fatal stabbing that happened that day in northeast Charlotte.
A 24-year-old man was charged with first-degree murder in the death Claudio Pedro Palomares, 43. Police said the two men shared a residence in the 4500 block of Perth Court, where the stabbing happened.
Investigators believe Palomares was killed during a fight between the two men. The suspect also was injured and stayed at the scene after calling 911.
Anyone with information about these cases is asked to call Crime Stoppers at 704-334-1600 or visit the Crime Stoppers website at charlottecrimestoppers.com.